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The trafficking of copper into specific intracellular targets is delivered by metallochaperones (Puig and Thiele, 2002

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Neurological disorders In conditions like Parkinsons and Alzheimers diseases, disruptions in cellular Ca 2+ regulating systems in the plasma membrane, ER, and mitochondria can manifest in synaptic dysfunction, decreased plasticity, and neuronal degeneration [286,287,288]

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