The detailed inclusion criteria are included as follows: (1) RCTs only, (2) studies written in English language only, (3) studies involving elderly individuals aged 60 years or older, (4) studies conducted on patients with Alzheimer's dementia in any setting or any country, and (5) studies using MB as an intervention for the treatment of Alzheimer's dementia
The use of a BPC peptide salt according to any of the claims 1 to 9 for the preparation of a compatible, storage-stable pharmaceutical composition according to claim 10 for the treatment of:disturbances connected with either nitric oxide (NO) formation or impaired NO-system functions, in particular, hypertension, angina, impotence, circulatory and septic shock, stroke, inflammation, respiratory distress syndrome, adhesion and aggregation of platelets and leukocytes, endothelial dysfunction, gastrointestinal lesions, peristalsis disturbances, diabetes pancreatitis, hypotension and Parkinson's disease;dysfunctions or hyperfunctions of somatosensory nerves, in particular, sensory neuropathy, postherpetic neuralgia, atopic dermatitis, impaired healing of injured tissue, acquired cold and heat urticaria, psoriasis, bullous pemphigoid, eczema, photodermatoses, chronic arthritis, gastrointestinal lesions and specific or non-specific hyperreactivity of upper and lower respiratory tracts (asthma, rhinitis);endothelium disturbances;wounds, ulcers;conditions relating to acute and/or chronic inflammation, in particular, chronic arthritis, and disorders related with delayed type of hypersensitivity, and gastrointestinal lesions;liver disorders, organ lesions induced by free radicals specifically caused by irradiation;disorders connected with cathecholaminergic system disturbances, in particular, schizophrenia, amphetamine challenge effects, drug abuse;stress related conditions;acute pancreatitis
Amylin has also been implicated in enhancing leptin signaling [47]
The peptide demonstrates remarkable stability in gastric juice, making it uniquely suited for gastrointestinal research applications
