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A systematic review of 32 population-based metabolomic studies utilizing plasma/serum, synovial fluid, cartilage, or subchondral bone samples has uncovered metabolic pathways implicated in OA, including energy metabolism, arginine and proline metabolism, taurine and hypotaurine metabolism, and glycerophospholipid metabolism [78]

its endogenous synthesis requires two essential amino acids (lysine and methionine) and the presence of optimal amounts of vitamin C, B6, and iron

One of the medical benefits of caffeoylquinic and dicaffeoylquinic acids is that they can fight viruses like adenovirus and herpes (Chiang et al

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