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Mean 24-hour Plasma Glucose Profiles (standardized meals) in Patients with Type 2 Diabetes before (Baseline) and after 12 Weeks of Treatment with Semaglutide or Placebo Insulin Secretion Both first-and second-phase insulin secretion are increased in patients with type 2 diabetes treated with OZEMPIC compared with placebo

Single-cell suspensions were generated by resuspending the organoid pellets in 500 L of accutase (Promega) per 1.5 mL low-binding tube and incubated at 37 C for 10 min