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In this review, we integrate these emerging insights with foundational knowledge by outlining the biology of HSP70s, with particular emphasis on recent discoveries, such as new data on the substrate specificity and molecular dynamics of HSP70client interactions

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Mineralocorticoids, whether in excess (Hyperaldosteronism) or in deficiency (Hypoaldosteronism), are linked to oxidative stress, mainly via activation of the renin-angiotensin-aldosterone system (RAAS) and disruption of cellular homeostasis due to sodium and potassium imbalances