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(2021) 11:e2021132

Increased mitochondrial oxidative stress in the Sod2 (+/-) mouse results in the age-related decline of mitochondrial function culminating in increased apoptosis

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Functional characterization of 26S-UIDs targeting CERT1 Having observed good IMPDH2 degradation activity using USP14-directed chimeras, in particular with 354 , and to assess whether long incubation times were required for degradation with USP14-recruited 26S-UIDs, we turned our attention to CERT1, a target in cancer 42