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Using this computational prediction method, we found that Gclc fl/fl MZB exhibited increased glucose catabolism compared to Gclc fl/fl FoB (Fig

Among the molecular mechanisms implicated in Nrf2-mediated malignancy acquisition in this tumour, stabilization of Bach1, a pro-metastatic transcription factor, has been described

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(2017) reported that long-term culture of HepG2 and Huh7 cells under physiological hypoxia (8% O) increased intracellular ROS and p66^Shc, correlating with greater migration, metabolic flexibility, and oxidative-stress resistance, hallmarks of an aggressive HCC phenotype [90]