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But these results have already had an immediate impact

Answer : The major players in the GLP-1 analogues market include Novo Nordisk, Eli Lilly and Company, Sanofi, AstraZeneca, Boehringer Ingelheim, Pfizer, Amgen, Roche, Zealand Pharma, Structure Therapeutics, Viking Therapeutics, Hangzhou Sciwind Biosciences, Fudan University, Eccogene, Medtronic, Merck & Co., AbbVie, Bayer AG, Teva Pharmaceutical Industries Ltd., and Boehringer Ingelheim

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Although we demonstrated our theoretical consideration on GPCR desensitization by limiting to a prototypical desensitization pathway, it is straight-forward to extend our formulation to include other pathways such as phosphorylation by cAMP-induced activation of PKA [73, 74], which requires including a feedback regulation, and dephosphorylation without internalization [56, 75] and so forth