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Dopamine (DA) receptor DRD2 and somatostatin (SS) receptors (SSTRs) represent the main targets of pharmacological treatment of pituitary tumors since they mediate inhibitory effects on both hormone secretion and cell proliferation, and their expression is retained by most of these tumors

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In obese mice, combining ERR activation with dietary control yields additive improvements in fat mass and hepatic features, suggesting compatibility with lifestyle or other pharmacological interventions