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Patients who switched from semaglutide to orforglipron maintained a mean 79.3% of their body weight reduction compared with the placebo arm which maintained a mean 37.6% of their weight loss

The peptide also slows gastric emptying, reduces appetite, and promotes weight loss

***Aunque con la intervencin siguieron con cifras por arriba de lo recomendado, en un 76% hubo disminucin de las cifras en un rango de 12-54 mg/dL

This adverse event occurred in the absence of a major cardiovascular risk factor, hemodynamic instability, or hypercoagulability state, thus excluding major conditions predisposing the onset of this acute event