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The full treatment cycle usually runs 12-16 weeks, followed by a break period before potential additional cycles

For companies that have historically focused on SBIR rather than STTR, Sims used the session to make a direct case for reconsidering that calculus given the new pathway

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Phase 2 trial data (Jastreboff et al., NEJM 2023) demonstrated average weight reductions of approximately 1724% over 48 weeks notably higher than currently approved GLP-1 receptor agonists such as semaglutide, though direct comparisons are limited by differences in trial populations and designs