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We have recently reported the effect of carbachol on nicotinic receptors, and since nicotinic receptors are expressed at sympathetic synapses, we administered carbachol 34

PMID: 30563192

It says these may indicate nutrient deficiency, dehydration, or an individual intolerance

These concerns necessitate further research, including dedicated long-term safety studies in animal models, specifically designed to assess potential risks associated with higher doses and prolonged exposure