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While NP4 remained relatively stable under physiological conditions, the payload was readily released in the presence of H 2 O 2 (Supplementary Fig

To confirm this, we performed a ChIP assay and found that ZHX2 protein was enriched at the promoter region of the YTHDF2 gene in Huh7 cells (Fig

The research evidence, while preclinical, is compelling

There are numerous factors that affect adherence, including patient and/or physician resistance to intensifying treatment regimens, financial burden, and the complexity of the medication regimen