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Though angiogenesis (growth of new blood vessels from preexisting vessels) is a normal and vital process in growth and development, it is also a fundamental step in the transition of tumors from a dormant state to a malignant one [4]

The carnitine pool plays an important role in cancer biology, which is not only closely related to the metabolic reprogramming of cancer cells [62, 63], but also involved in the crosstalk between immune cells and the tumor microenvironment, affecting the immune escape mechanism of tumors

Hyclone, Logan, UT, USA) supplemented with 20% fetal bovine serum (FBS

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