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5), and by inference, neurotoxic damage.53 Forgione and colleagues had previously hypothesized that GPX1 deficiency directly induces an increase in vascular oxidative stress, with attendant endothelial dysfunction.54 Glutathione peroxidases, particularly GPx1 have also been implicated in the development and prevention of many common and complex diseases, including cancer and cardiovascular disease (Fig

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Improved Drug Delivery to the Brain One of the major challenges in the treatment of neurodegenerative disorders is the brain blood permeability which limits the delivery of drugs into the brain

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