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Notwithstanding progress in diabetic retinopathy treatments, such as laser photocoagulation, intravitreal anti-VEGF therapy, and corticosteroids, treatment is constrained by exorbitant costs, intrusive techniques, unpleasant effects, and inconsistent patient responses

Take care to avoid duplicate paracetamol products and use with caution if you have liver disease or alcohol misuse

Symptoms appear within the first few weeks, peak during weeks 6-8 (coinciding with dose escalation), and resolve substantially by week 12

This protective effect is mediated through the activation of the Nrf2 pathway, which upregulates key antioxidant proteins, including GPX4, HO-1, TFR1, and FTH1, thereby mitigating ferroptosis (55)