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Interruptions and Discontinuation Increase Cardiovascular Risk Moreover, longer discontinuation was progressively associated with elevated MACE risk, with IRRs of 1.14 for one year of discontinuation and 1.22 for two years

Exenatide once-weekly clinical development: Safety and efficacy across a range of background therapies

In April 2005 the US Food and Drugs Administration (FDA) approved a synthetic version, called exenatide, to treat type 2 diabetic patients unable to sufficiently control their blood sugar levels with other diabetic medications like metformin, and sulfonylureas

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