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Although these macrocycles cannot activate Met signalling per se , they become effective agonists after dimerization by appropriate cross-linkers and specifically activate Met-related downstream signalling pathways

This is a simple approach, as these drugs leave traces in the urine when they pass out of the body

The reason is that the source of these compounds is derived from living organisms through enzymatic polymerization, forming high molecular weight macromolecules

Die lyophilisierte Durchstechflasche wird bei Raumtemperatur gelagert, geschtzt vor Licht und Feuchtigkeit ohne dass eine Khlung vor der Rekonstitution erforderlich ist