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The detail is contained within two recent publications in prestigious, peer-reviewed medical journals: Doctors at the University of North Carolina in America conducted a small clinical trial of GLP-1 in pouchees who had a high frequency of bowel movements but with a normal pouch (i.e., no inflammation)

While 2.4 mg is the FDA-approved maintenance dose for semaglutide, not everyone needs the absolute max to achieve substantial weight loss