Toosy S, Sodi R, Pappachan JM
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On the other hand, it efficiently delivers p65 siRNA to target and silence NF-B, thus reducing hepatocyte injury markers (ALT/AST), suppressing the release of inflammatory factors, and significantly ameliorating acute liver injury by targeting this central inflammatory pathway (Yin et al., 2023)
Mol Cell 14(3):395403 Latres E, Amini AR, Amini AA, Griffiths J, Martin FJ, Wei Y, Lin HC, Yancopoulos GD, Glass DJ (2005) Insulin-like growth factor-1 (IGF-1) inversely regulates atrophy-induced genes via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) pathway