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Some microbial metabolites, such as phenylacetate, had been implicated in women with obesity in lipids accumulation in liver, thus contributing to Non-alcoholic steatohepatitis (NASH) development

44 Recent findings have shed light on how iron overload affects cardiac mitochondrial function, leading to reduced mitochondrial respiration, increased synthesis of ROS, mitochondrial membrane depolarization, and mitochondrial swelling, which affect the mitochondrial fission and fusion process

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I would recommend not isolating to one or two supplements but a whole host of supplements