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Seventh, these results should not be applied to patients with primary carnitine deficiency (typically arising from genetic alterations in renal handling or muscle transport of L-carnitine) or secondary carnitine deficiency (typically arising from impaired renal tubular resorption from drug toxicity or hemodialysis)

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Men's doses are usually subcutaneously injected at daily doses of between 0.2 and 0.5 mg

Thiazolidinediones (such as pioglitazone) improve insulin sensitivity through a different mechanism and are sulfonamide-free, though their use has declined due to side effect profiles