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GLP-1s are changing obesity care but nutrition may be the silent side effect. As Jorge Urbina and colleagues highlight in a 2026 Clinical Obesity narrative review, GLP-1 receptor agonists (e.g., semaglutide, liraglutide, tirzepatide) can predispose some patients to micronutrient and nutritional deficienciesvia appetite suppression, delayed gastric emptying, and altered intake/absorption

is to be preferred since, in our experience, it is always free of interferences

Individuals with a history of liver disease, liver tumors, breast cancer or other hormone-sensitive cancers should avoid using Mirena

A practical clinical approach might include checking fasting insulin and HOMA-IR alongside standard glucose screening