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Is glutathione IV therapy safe

Proceedings of the Royal Society of London 77(519):405-420. [doi.org]

Nocturnal enuresis (a pediatric indication - attributed to its antimuscarinic side effects) Contraindications: Drugs that inhibit monoamine oxidase (MAOI's) taken w/in 14 days, acute recovery period after a myocardial infarction, or history of drug hypersensitivity Side Effects: drowsiness dry mouth & eyes constipation orthotstatic hypotension mild tremor sweating agitation nausea tinnitus Overdose & Treatment: See Amitriptyline

This led to FDA black box warnings requiring screening for glucose intolerance before starting treatment and periodic monitoring during treatment, with recommendations against use in patients with poorly controlled diabetes