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Extracellular Matrix Remodeling BPC-157 influences the expression of matrix metalloproteinases (MMPs) and their inhibitors, playing a role in matrix stability and remodeling during injury repair and chronic inflammation

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The study found that FOXO4 localizes predominantly in the cytoplasm of Leydig cells in young mice but translocates to the nucleus in aged animals the same FOXO4-p53 sequestration pattern seen in other senescent cell types

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