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NB-ER and GLP-1 combination therapy can be one of the potential options in this approach. MNT had the opportunity to speak with Mir Ali, MD, a bariatric surgeon and medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in Fountain Valley, CA, about the recent review

The most significant concern relates to gastrointestinal adverse effects

10.1016/j.jot.2023.02.003 Summary Keywords GLP-1, semaglutide, osteogenic differentiation, LRP5, signaling pathway Citation Tian Y, Liu H, Bao X and Li Y (2025) Semaglutide promotes the proliferation and osteogenic differentiation of bone-derived mesenchymal stem cells through activation of the Wnt/LRP5/-catenin signaling pathway

Gut microbiota and glucometabolic alterations in response to recurrent partial sleep deprivation in normal-weight young individuals