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Acetaminophen sales were high in English-speaking countries, and were positively associated with asthma symptoms, eczema and allergic rhinoconjunctivitis in children aged 1314, and with wheeze, diagnosed asthma, rhinitis and bronchial responsiveness in adults

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33 CONCLUSION While these findings are encouraging, especially for diseases such as psoriasis and HS in which patients often are heavier and may have comorbidities like type 2 diabetes, insulin resistance, or metabolic syndrome, its important to recognize that most data to date come from small observational or retrospective studies with multiple possible confounders