Our study is among the first to provide compelling evidence that low testosterone can be reversed with the use of commonly prescribed anti-obesity medications. Portillo Canales team analyzed the records of 110 adult men with obesity or Type 2 diabetes taking the weight-loss medications semaglutide (Wegovy), dulaglutide (Trulicity) or tirzepatide (Zepbound) but not participating in testosterone or hormonal therapy
Mitchell JL, Lyons HS, Walker JK, Yiangou A, Grech O, Alimajstorovic A et al (2023) The effect of GLP-1RA exenatide on idiopathic intracranial hypertension: a randomized clinical trial
We also observed significant (1.9 and 1.2 times) increases in cellular GSH as a result of supplementing with exogenous GSH on pyocyanin + GSH-treated, and control + GSH-treated A549 cells, respectively
Furthermore, a cKO model of HGF deregulation, in which HGF was deleted from a limited number of tissues including cochlea, was associated with extensive cochlear pathology with morphogenetic defects and non-progressive deafness (Schultz et al., 2009)