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Phase 1 is believed to correspond to the high level of activity in the primary afferent as by C-fiber activation due to peripheral stimulation, 9 whereas phase 2 seems to result from the continuous low level of small afferent input, together with a facilitated state of spinal processing

Summary: Vitamin D and B12 are distinct essential nutrientsvitamin D regulates calcium metabolism and bone health, whilst B12 supports DNA synthesis, red blood cell formation, and neurological function

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