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Combining Dihexa with dopaminergic stimulants (modafinil, amphetamines) doesn't require dose adjustment but may mask fatigue signals that would otherwise indicate overtraining of cognitive circuits

doi: 10.1016/j.jphs.2020.07.014

Our results provide a near-atomic level visualization of the molecular action of multi-targeting agonists on three cognate receptors and offer valuable information for the design of better drugs to combat metabolic diseases