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Emerging evidence also suggests that metformin promotes mitophagy and mitochondrial biogenesis, further limiting mtDNA release and neuroinflammation [206,207,208]

doi: 10.3803/EnM.2014.29.4.536 70 KrnerMStckliMWaserBReubiJC

[17] If NSAIDs are necessary, they should be used at the lowest effective dose for the shortest duration, and patients with renal impairment should seek medical advice before use

Vitamin D is a fat-soluble vitamin that is naturally present in very few foods, added to others, and available as a dietary supplement