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Note whether the change is brief and tied to activity, anxiety, or a dose increase

European patients still need to perform a high-volume injection, but they will use either a unit-dose or a multiple-dose disposable delivery device

Frail patients routinely get undertreated because clinicians fear they wont tolerate medications well. With such promising findings, Pandey says the teams next step is confirming these results with objective physical measures: the Fried frailty phenotype, Short Physical Performance Battery, grip strength, gait speed

Subcutaneous administration minimizes these effects by reducing required dose and avoiding first-pass gut metabolism [8]