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Together, these primary data delineate a pathogenic axis spanning focal iron accumulation, peripheralcentral iron imbalance, and ferroptosis susceptibility in early AD. Further evidence shows that ferritin levels in cerebrospinal fluid (CSF) can predict the rate of cognitive decline and are significantly associated with both A-positivity on PET imaging and elevated t-Tau concentrations

[DOI] [PMC free article] [PubMed] [Google Scholar] 51.Padayatty S.J., Katz A., Wang Y., Eck P., Kwon O., Lee J.-H., Chen S., Corpe C., Dutta A., Dutta S.K., et al

In a 2023 animal model, GHK-Cu accelerated diabetic wound closure by 40% via PI3K/Akt signaling (Zhang et al., 2023)

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