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GLP1/E therapy led to upregulation of pathways involved in autophagy and vesicle-mediated transport, suggesting that this intervention enhances hypothalamic autophagy, a mechanism that may contribute to the metabolic improvement observed in GLP1/E-treated animals

It also plays a significant role in energy metabolism in the body

Additionally, most studies have focused on individuals with co-occurring obesity or diabetes, limiting generalisability to the broader population with alcohol use disorder

This can also be seen in the so-called Ozempic Butt phenomenon, where significant deflation in the gluteal area can result in flat, poorly-defined buttocks