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Its mechanism targets appetite regulation and gastric motility rather than direct insulinotropic effects

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In addition, semaglutide has been shown to have greater appetite suppressive effects than liraglutide in overweight individuals and so may also be better at suppressing hyperphagia in lipodystrophy ( Another key potential advantage of GLP-1R agonists for lipodystrophy patients is the availability of both long acting and oral GLP-1R agonists ( Despite clear advantages to GLP-1R agonist use in lipodystrophy presented here, some patients with lipodystrophy also develop pancreatitis