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Studies have shown that ACSL4-enriched exosomes can be phagocytosed by microglia, leading to the activation of the nuclear factor kappa-B (NF-B) signaling pathway and polarization of microglia toward a proinflammatory M1 phenotype, thereby amplifying neuroinflammation (He et al., 2024)

270-272 A review of 12 studies of lysine supplementation in the treatment or prevention of herpes outbreaks found that doses below 1 g/day were ineffective unless combined with a low-arginine diet

Methylcobalamin stands out as it can be readily used in metabolic functions without needing conversion, making it an efficient option for addressing issues such as cognitive impairment

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