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Patients are "better served" by an expert, such as a weight-loss physician or primary care doctor, who can closely monitor them while taking these drugs, the doctor suggested, especially with the risk of certain side effects, like nausea or pancreatitis

High-resolution structural images of retatrutide bound to each of the three receptors, published in 2024, confirmed that one peptide can dock into three different receptor sites, providing the physical basis for the triple-receptor approach [3]