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Glossary Triple Agonist A compound that simultaneously activates three distinct receptor types

To that end, DHEA may:6 Interact with prescription medications (particularly those for mental health, including SSRIs, antipsychotics, carbamazepine, lithium, and valproic acid) Worsen psychiatric disorders and increase the risk of mania in people with mood disorders Reduce HDL (good) cholesterol levels Increase the risk of hormone-sensitive cancers (prostate, breast, and ovarian) Lead to oily skin, acne, or hirsutism in women (male-pattern hair growth) For more information on the potential drug interactions, you can find extensive lists from the Mayo Clinic and Mount Sinai

however, when handled as a research chemical: Effects are dependent on concentration, exposure conditions, and experimental model High concentrations in vitro may alter cellular redox balance and produce unintended experimental outcomes Long-term effects in experimental systems depend on study design and conditions Handling Precautions: Use appropriate personal protective equipment (PPE) including gloves, lab coat, and eye protection Avoid inhalation, ingestion, or direct contact with skin and eyes Handle under controlled laboratory conditions using standard safety protocols Regulatory Status: Not approved by the U.S

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