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Cross-Study Findings Experience With Dosing Greater Than 10 g Of Hydroxocobalamin Across all four uncontrolled studies, 10 patients who did not demonstrate a full response to 5 or 10 g-doses of hydroxocobalamin were treated with more than 10 g of hydroxocobalamin

Based on the similarity to the three repeat sequences R1, R2, or R3 in animal c-myb and the number of R repeat sequences, the plant MYB TFs family has been classified into four categories: MYB TFs are classified as 1R-MYB, R2R3-MYB (majority), R3-MYB, R4-MYB and MYB-like (MYB-related) ( Figure 3 ) (Dubos et al., 2010)

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