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Amputations for extremity soft tissue sarcoma in an era of limb salvage treatment: local control and survival

NICE guidance on obesity (CG189: Obesity: identification, assessment and management) and lifestyle weight management services (PH53) emphasises structured lifestyle interventions, behavioural support, and where clinically appropriate pharmacological treatment prescribed by a clinician, rather than over-the-counter supplements

Compared with EtOH-fed WT mice, KO mice were less susceptible to EtOH-induced deleterious effects, including body weight loss (reflected by less body weight gain), liver weight gain and hepatocyte damage (reflected by plasma ALT activity) (Table 1)