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[note 16] [175] Toxicity In rodents and primates, sufficiently high doses of amphetamine cause dopaminergic neurotoxicity, or damage to dopamine neurons, which is characterized by dopamine terminal degeneration and reduced transporter and receptor function

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The GLP-1 receptor (GLP-1R) is widely expressed in various systems, including adipose tissue, the cardiovascular system and the gastrointestinal tract [26]