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However, several limitations may preclude the use of Fer-1 and Lip-1 in clinical settings, including their possible unsatisfactory pharmacokinetics and pharmacodynamics profiles

128,129 Conversely, USP4, USP10, and USP18 mitigate metabolic dysfunction by reducing hepatic steatosis, hyperglycemia, and inflammation, suggesting therapeutic potential against MASLD and T2DM

however, no optimal reagent for skin chemical burns currently exists