During the study, patients with intestinal inflammation who were given NAC experienced less inflammation, reduced oxidative stress, an improvement in energy levels, and repair to intestinal tissue damage
Thus, glutamine metabolism is intriguingly linked with intricate cell metabolic processes via enzymes associated with mitochondrial glutaminolysis, cytosolic glutamine metabolism, and glutamine-derived metabolites that perform diverse cellular functions
While mTORC2 primarily promotes cell proliferation and survival through the phosphorylation of AKT, many tumors need mTORC1 to maintain their ability to control protein synthesis and cell growth, as well as to coordinate nutrient and energy supply to ensure that they undergo unrestricted cell division (103)
Golbidi S, Ebadi SA, Laher I