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Should we ignore studies that have less than X number of subjects

Babaev VR, Li L, Shah S, Fazio S, Linton MF, May JM

Here we determined the rate constants for the individual redox reactions between the two redox-sensitive cysteinyl residues of roGFP2 and the active-site cysteinyl residues of the model class I glutaredoxin PfGrx from the malaria parasite Plasmodium falciparum using stopped-flow kinetic measurements in combination with redox mobility shift assays

However, patients with pre-existing glutathione deficiency, malnutrition, liver compromise, or genetic variations affecting detoxification enzymes may experience greater depletion impact and warrant more cautious use or provider oversight