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Astrocytic alterations have also been implicated in SCZ, with reports of changes in astrocytic density, morphology, and the expression of markers such as glial fibrillary acidic protein (GFAP), aquaporin-4 (AQP4), S100, glutaminase, thrombospondin-1 (TSB-1), and excitatory amino acid transporter 2 (EAAT2

1517 Early-life determinants, which includes mode of delivery, infant feeding practices, and antibiotic exposure, could shape microbial communities and are strongly linked to later obesity risk, underscoring the long-term impact of microbiota development on metabolic outcomes

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