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LPS and ox-LDL, both associated with oxidative stress and vascular inflammation, promote NF-B activation, further repressing eNOS expression (Liao et al., 1995

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BYDUREON BCISE-treated patients that had higher titer antibodies had a lower glycemic response compared to BYDUREON BCISE-treated patients who did not have anti-exenatide antibodies during the treatment period [see Warnings and Precautions (5.6)]