Key Takeaways GLP-1 is your body's natural "I'm full" hormone, and lower levels might contribute to weight gain If you're dealing with perimenopause or postmenopause weight gain, cravings, blood sugar issues, or insulin resistance, extra support can help with achieving and maintaining a healthy weight There's limited evidence that some supplements like fiber, probiotics, and berberine might help boost GLP-1 levels, though they can support weight loss in other more well-researched pathways
This is approximately one-tenth of the full therapeutic dose of 2.4 mg used in the STEP clinical trials for weight management
For others, metabolic effects and calorie expenditure may play a larger role
Moreover, GIP at pharmaceutical doses may prevent atherosclerosis, causing obesity, and the positive benefits of GIP may also be maintained in animals [39]