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More comprehensive insight into the effects of GLP-1 RAs on gastrointestinal and central nervous system functions is required

Chronische Nierenerkrankung Bei Patienten mit Diabetes mellitus sind die Blutzuckerwerte erhht und es fliet mehr Glukose durch das Glomerulum der Niere

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Mechanisms of Glycemic Control (The Pancreas) The primary mechanism for glycemic control involves the activation of GLP-1 receptors (GLP-1R) on pancreatic islet cells, initiating intracellular signaling cascades such as the cAMP/PKA and PI3K/Akt pathways (Figure 1)(Zheng et al., 2024)