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This meant that GLP-1RA could not only indirectly mediate M2 polarization of microglia by regulating Tregs, but also directly bind to GLP-1R on the membrane surface of microglia, completing M2 polarization through the GLP-1R/cAMP/PKA/IL-10 signaling pathway ( Recent research showed that GLP-1RA could reduce plasma TNF- levels induced by different Toll-like receptor agonists and significantly inhibit neuroinflammation (98)

Ophiopogonin D improves osteointegration of titanium alloy implants under diabetic conditions by inhibition of ROS overproduction via Wnt/-catenin signaling pathway

[7] Given that certain Staphylococcus species are responsible for thioalcohol production (the sulfurous component of armpit odor), strains with anti-staphylococcal properties are mechanistically relevant here

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