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Circulating IGF-1 LR3 reaches all tissues simultaneously, activating IGF-1 receptors system-wide without the preferential hepatic routing inherent to HGH mechanisms

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Rheumatoid arthritis (RA) is the prevalent form of chronic inflammatory arthritis, affecting 1% of the population, characterized by synovial hyperplasia and infiltration of inflammatory cells in the synovial tissues 5,6

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